@Leslie_M ...thrombologists. They're wrong. I personally encountered and reported the impact long before it was medically proven. Now it has been. Both Coumadin and Tylenol metabolize in the liver, so there can be a compounding, dangerous anticoagulation e
Saw another case recently of this under appreciated interaction between warfarin and acetaminophen.
التعارض بين الوارفرين وال اسيتامينوفين case report 👇
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
Yes! Pharmacists take note too. NSAIDs were always hammered into us as the risky analgesic for patients on warfarin, but acetaminophen’s interaction with warfarin can also be clinically significant. 💊 🩸 #PHAR4902F22
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
RT @tsengeric: Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors s…
Just cited this classic @CMAJ case report in a consult note. All hematologists, internists, hospitalists, family doctors should read this. The interaction between warfarin and tylenol is clinically signficant!!! @Pete_Wu @Derek_Leong_RPh https://t.co
الاسيتامينوفين من المسكنات شائعة الاستخدام OTCوالتي تتعارض بشكل ملحوظ مع الوارفارين في PD مما يؤثر علىINRويزيد فرصة النزيف، لكل المطمئن ان العرض يعتمد على الجرعة والمدة. هذه الورقه تناقش حالة لمريضة حصل لها هذا التفاعل الدوائي، للمهتمين🩸🫀، قراءة ممتعة 👍 ht
RT @ph_minimal: @Fizz_DI これ一本、チラ見しただけですが、NAPQIが絡みそうですね。NAPQIが蓄積しなそうな症例でも相互作用を起こすのかが気になるところ…。 INRへの影響の度合いに用量・飲酒・2E1などが関わってくるんですかねぇ🤔 https:…
RT @ph_minimal: Warfarin and acetaminophen interaction in a 47-year-old woman - PubMed NAPQIがらみの薬力学的なやーつ なのかな https://t.co/v2NeKhGSqv
@Fizz_DI これ一本、チラ見しただけですが、NAPQIが絡みそうですね。NAPQIが蓄積しなそうな症例でも相互作用を起こすのかが気になるところ…。 INRへの影響の度合いに用量・飲酒・2E1などが関わってくるんですかねぇ🤔 https://t.co/DFMHhYPz29
RT @ina_yurui: @aiurotips NAPQIが影響してるようです。初めて知りました。 https://t.co/TO95VRUzMc
RT @ina_yurui: @aiurotips NAPQIが影響してるようです。初めて知りました。 https://t.co/TO95VRUzMc
Warfarin and acetaminophen interaction in a 47-year-old woman - PubMed NAPQIがらみの薬力学的なやーつ なのかな https://t.co/v2NeKhGSqv
#معلومة يزيد (Paracetamol) من تاثير (warfarin) يزيد هذا الاحتمال عند اخذ الباراسيتامول بجرعات كبيرة (day/2g-1.3 g) وبانتظام. قد يكون الامر بحاجة لضبط جرعة الوارفارين 🚨 https://t.co/OpWM4usKjk https://t.co/BSRFY8xHEK
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: @PharmaFactz Acetaminophen
@PharmaFactz Acetaminophen
RT @erdocmom: I did not know this. How many patients on Coumadin have we casually instructed to take Tylenol for pain over the years? https…
I did not know this. How many patients on Coumadin have we casually instructed to take Tylenol for pain over the years? https://t.co/GX0qv9ts5q
Informative cautionary tale about acetaminophen causing high INR In patient on warfarin. https://t.co/dtkKZH6uD4
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @Derek_Leong_RPh: Very happy to announce with @Pete_Wu that our case report highlighting an important acetaminophen-warfarin DDI was pub…
RT @kori_leblanc_Rx: Important findings for #Pharmacists Thanks @Derek_Leong_RPh @Pete_Wu
RT @Pete_Wu: It's a thing! Our case report where acetaminophen and warfarin ➡️ 📈INR @Derek_Leong_RPh @CMAJ
RT @IslaMacaninch: Really?? Paracetamol??
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @amillsRx: Great work Derek. Congrats https://t.co/yQcJ8NiDpX
Great work Derek. Congrats
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
Another reason to reserve VKA for mech valves and assorted limited indications!
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @CMAJ: Warfarin, a blood thinner, and acetaminophen interacted to cause severe internal bleeding in this case of a 47-year-old woman wit…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
Have seen a patient who’s INRs were stable with 2g daily of Tylenol. When it increased to 3G INR jumped dramatically!
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
Mind = 💥
Great review by @Pete_Wu and @Derek_Leong_RPh! Just saw a case two weeks ago in er. Increased Tylenol use for arthritis. Inr >10 with gi/gu bleed.
warfarin education materiel need updating !
Acetaminophen increases INR https://t.co/GVyGwozl0v
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
Important findings for #Pharmacists Thanks @Derek_Leong_RPh @Pete_Wu
Bravo! Bravo! Bravo! #FOAMed
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…
RT @DavidJuurlink: Acetaminophen can dramatically increase the INR in patients on warfarin. Congratulations to @Pete_Wu and @Derek_Leong_RP…