RT @Fizz_DI: 併用禁忌ではない「アロプリノール×アザチオプリン」の同時使用でも、アザチオプリンの副作用が増強され重度の貧血が起きたと考えられる症例。 CMAJ.193(3):E94-E97,(2021) PMID:33462145 https://t.co/KN…
RT @Fizz_DI: 併用禁忌ではない「アロプリノール×アザチオプリン」の同時使用でも、アザチオプリンの副作用が増強され重度の貧血が起きたと考えられる症例。 CMAJ.193(3):E94-E97,(2021) PMID:33462145 https://t.co/KN…
併用禁忌ではない「アロプリノール×アザチオプリン」の同時使用でも、アザチオプリンの副作用が増強され重度の貧血が起きたと考えられる症例。 CMAJ.193(3):E94-E97,(2021) PMID:33462145 https://t.co/KN6j5tKEN4
アロプリノールのようなキサンチン酸化酵素阻害薬でアザチオプリンの骨髄毒性代謝物が増加し重症貧血、白血球減少のケース。併用する場合はAZAの低用量(単剤投与量の約25~50%)を使用し、血球をモニターすることが推奨されている。ACE-Iも相互作用あるんですね。 https://t.co/9CT8Nx79Xi
Congratulations to Drs. @LorenzoMadrazo, Jones and Hsia on their publication!
RT @LorenzoMadrazo: Thankful that our team was able to write about this patient's story and share this important teaching pearl about drug-…
RT @CMAJ: Drs. @LorenzoMadrazo, Emily Jones and Cyrus Hsia discuss the link between azathioprine and #anemia and how interactions with othe…
RT @LorenzoMadrazo: Thankful that our team was able to write about this patient's story and share this important teaching pearl about drug-…
RT @CMAJ: Drs. @LorenzoMadrazo, Emily Jones and Cyrus Hsia discuss the link between azathioprine and #anemia and how interactions with othe…
Thankful that our team was able to write about this patient's story and share this important teaching pearl about drug-drug interactions through this case report! @CMAJ I'm glad the patient did well and that we were able to figure out the cause of his a
Drs. @LorenzoMadrazo, Emily Jones and Cyrus Hsia discuss the link between azathioprine and #anemia and how interactions with other drugs like allopurinol can amplify its effects: https://t.co/935KYXWYoy #FOAMed #Haematology #Hematology #Pharmacology https: